About PI (Chen, Po-Han/ 陳伯翰)
Po-Han was born and raised in Taipei, Taiwan. His research career started at Prof. Hsin-Chih Lai’s Lab (Chang Gung University) to study bacteria physiology as an undergraduate student. His master thesis, focused on RNA splicing and fly development, was advised by Prof. Show-Li Chen at National Taiwan University. In 2013, he received the Hung Taiwan-Duke fellowship to begin his PhD at the Dept. of Molecular Genetics and Microbiology at Duke University in the United States. While focusing on the Blue Devil's game day (Go Duke!), Po-Han was also co-mentored by Prof. Jen-Tsan Ashley Chi (Molecular Genetics and Microbiology) and Prof. Michael Boyce (Biochemistry) to learn complementary skills in genetics and biochemistry. His PhD works uncovered novel biological determinants in two emerging topics, ferroptosis and O-GlcNAcylation. For post-doctoral training, he changed his research trajectory to learn chemical biology with Prof. Craig M. Crews at Yale University. The Crews lab is the world-leading lab for the PROTAC (proteolysis targeting chimera) technology. Other than working on the development of PROTACs, Po-Han has pioneered a novel catalytic drug modality using bifunctional molecules (PhosTACs, phosphorylation targeting chimera) for targeted protein dephosphorylation. Education
2004-2008, B.S., Medical Technology, National Taiwan University, Taipei, Taiwan學士/醫學檢驗暨生物技術學系/台灣大學/台北/台灣2008-2010, M.S., Graduate Institute of Microbiology, National Taiwan University, Taipei, Taiwan碩士/微生物學研究所/台灣大學/台北/台灣 2013-2018, Ph.D., Molecular Genetics and Microbiology, Duke University, Durham, NC, U.S.A.博士/分子遺傳暨微生物學所/杜克大學/德罕/北卡羅萊納/美國Professional Experiences
2010-2011, Medical Technologist, Hualien Armed Force Hospital, Hualien, Taiwan 少尉醫檢師/花蓮國軍總醫院/花蓮/台灣2011-2013, Research Assistant, Graduate Institute of Microbiology, National Taiwan University, Taipei, Taiwan研究助理/微生物學研究所/台灣大學/台北/台灣 2019-2022, Postdoctoral Associate, Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT, U.S.A.博士後研究員/分子細胞發育生物學所/耶魯大學/紐哈分/康乃狄克/美國 August 2022- present, Assistant Professor, Dept. Biochemistry and Molecular Biology, National Cheng Kung University, Tainan, Taiwan助理教授/生物化學暨分子生物學研究所/成功大學/台南/台灣
Honors, Awards, and Funding
1. 2013, Graduate Student Research Award, College of Medicine, National Taiwan University2. 2013-2014, Hung-Taiwan Duke University Fellowship3. 2017, Duke MGM Chairman Travel Award4. 2018, Duke Graduate School Travel Award5. 2020, Life Science Research Foundation Fellowship Finalist6. 2022-2026, 2030 Cross-Generation Young Scholars Program (Emerging Young Scholar), National Science and Technology Council, Taiwan (2030跨世代年輕學者-新秀學者/國家科學及技術委員會/台灣)7. 2023-2024 新進人員研究補助計畫 (成功大學)8. 2023-2024永續跨領域整合型計畫 (成功大學/共同主持人)9. 2024-2027, National Health Research Institutes in Taiwan, Career Development Grant (CDG)（國家衛生研究院個人型研究發展獎助計畫/台灣)